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DCGI gives permission to Bharat Biotech for intranasal COVID booster dose trial

KV Prasad Jun 13, 2022, 06:35 AM IST (Published)

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Summary

India is yet to approve the use of Bharat Biotech’s intranasal vaccine, BBV154. In August, BBV154 had received regulatory approval for mid- to late-stage trials.

The Drugs Controller General of India (DCGI) on Friday gave permission to Bharat Biotech for intranasal COVID booster dose trials. The trials will be done at nine different sites.

Bharat Biotech had in December said that it has submitted an application to the DGCI to in this regard. “We have submitted phase 3 clinical trial application to DCGI,” a Bharat Biotech spokesperson said in a statement, adding that an intranasal vaccine as a booster dose will be easier to administer in mass vaccination campaigns.

India is yet to approve the use of Bharat Biotech’s intranasal vaccine, BBV154. In August, BBV154 had received regulatory approval for mid- to late-stage trials. There were reports that the mid-stage trial has been completed.

Krishna Ella, the chairman of Bharat Biotech, had earlier said the company is focusing on the intranasal vaccine as existing vaccines require two-dose intramuscular injections and a country like India needs 2.6 billion syringes and needles which may add to pollution. An intranasal vaccine will not only be simple to administer but reduce the use of medical consumables such as needles, syringes, etc significantly impacting the overall cost of a vaccination drive, he had said.

Covaxin, the company’s COVID-19 vaccine was approved for emergency-use approval in the county, is administered through an injection.

With inputs from agencies

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index Price Change
nifty 50 ₹16,986.00 -72.15
sensex ₹1,882.60 +28.30
nifty IT ₹2,206.80 +30.85
nifty bank ₹1,318.95 -14.95
index Price Change
nifty 50 ₹16,986.00 -7.15
sensex ₹1,882.60 +8.30
nifty IT ₹2,206.80 +3.85
nifty bank ₹1,318.95 -1.95
index Price Change
nifty 50 ₹16,986.00 -72.15
sensex ₹1,882.60 +28.30
nifty IT ₹2,206.80 +30.85
nifty bank ₹1,318.95 -14.95
index Price Change
nifty 50 ₹16,986.00 -7.15
sensex ₹1,882.60 +8.30
nifty IT ₹2,206.80 +3.85
nifty bank ₹1,318.95 -1.95
index Price Change
nifty 50 ₹16,986.00 -7.15
sensex ₹1,882.60 +8.30
nifty IT ₹2,206.80 +3.85
nifty bank ₹1,318.95 -1.95

Currency

Company Price Chng %Chng
Dollar-Rupee 73.3500 0.0000 0.00
Euro-Rupee 89.0980 0.0100 0.01
Pound-Rupee 103.6360 -0.0750 -0.07
Rupee-100 Yen 0.6734 -0.0003 -0.05
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Covishield, Covaxin receive regular market approval for use in adult population

KV Prasad Jun 13, 2022, 06:35 AM IST (Published)

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Summary

The Drugs Controller General of India’s (DCGI) approval came after the Subject Expert Committee (SEC) on COVID-19 of the Central Drugs Standard Control Organisation (CDSCO) on January 19 recommended granting regular market approval to the Serum Institute of India’s (SII’s) Covishield and Bharat Biotech’s Covaxin for use in adult population subject to certain conditions.

India’s drug regulator on Thursday granted regular market approval for COVID-19 vaccines Covishield and Covaxin for use in the adult population subject to certain conditions, official sources said. The approval was granted under the New Drugs and Clinical Trials Rules, 2019. Under the conditions, the firms shall submit data of ongoing clinical trials and the vaccines to be supplied for programmatic setting besides recording all vaccinations done within the country on the CoWIN platform, the sources said.

Adverse event following immunisation will continue to be monitored as part of the conditions. The Drugs Controller General of India’s (DCGI) approval came after the Subject Expert Committee (SEC) on COVID-19 of the Central Drugs Standard Control Organisation (CDSCO) on January 19 recommended granting regular market approval to the Serum Institute of India’s (SII’s) Covishield and Bharat Biotech’s Covaxin for use in adult population subject to certain conditions.

Prakash Kumar Singh, Director, Government and Regulatory Affairs at SII, had submitted an application to the DCGI on October 25 seeking regular market authorisation for Covishield. The DCGI had sought more data and documents from the Pune-based company following which Singh recently had submitted a response along with more data and information.

Also Read | Each dose of Covishield, Covaxin likely to be capped at Rs 275 after getting regular market approval

“Such a large-scale vaccination with Covishield and containment of COVID-19 infection is in itself a testimony of the safety and efficacy of the vaccine,” he had said. In an application sent to the DCGI, V Krishna Mohan, whole-time director at the Hyderabad-based Bharat Biotech, submitted complete information regarding chemistry, manufacturing and controls, along with the pre-clinical and clinical data while seeking regular market authorisation for Covaxin.

Bharat Biotech International Limited (BBIL) took up the challenge to develop, produce and clinically evaluate a vaccine (Covaxin), from the SARS-CoV-2 strains isolated from COVID-19 patients in India, Mohan had said in the application. Covaxin and Covishield were granted Emergency Use Authorisation (EUA) on January 3.

Also, catch all the live updates on COVID-19 situation with CNBC-TV18.com’s blog

Elon Musk forms several ‘X Holdings’ companies to fund potential Twitter buyout

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index Price Change
nifty 50 ₹16,986.00 -72.15
sensex ₹1,882.60 +28.30
nifty IT ₹2,206.80 +30.85
nifty bank ₹1,318.95 -14.95
index Price Change
nifty 50 ₹16,986.00 -7.15
sensex ₹1,882.60 +8.30
nifty IT ₹2,206.80 +3.85
nifty bank ₹1,318.95 -1.95
index Price Change
nifty 50 ₹16,986.00 -72.15
sensex ₹1,882.60 +28.30
nifty IT ₹2,206.80 +30.85
nifty bank ₹1,318.95 -14.95
index Price Change
nifty 50 ₹16,986.00 -7.15
sensex ₹1,882.60 +8.30
nifty IT ₹2,206.80 +3.85
nifty bank ₹1,318.95 -1.95
index Price Change
nifty 50 ₹16,986.00 -7.15
sensex ₹1,882.60 +8.30
nifty IT ₹2,206.80 +3.85
nifty bank ₹1,318.95 -1.95

Currency

Company Price Chng %Chng
Dollar-Rupee 73.3500 0.0000 0.00
Euro-Rupee 89.0980 0.0100 0.01
Pound-Rupee 103.6360 -0.0750 -0.07
Rupee-100 Yen 0.6734 -0.0003 -0.05
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Each dose of Covishield, Covaxin likely to be capped at Rs 275 after getting regular market approval

KV Prasad Jun 13, 2022, 06:35 AM IST (Published)

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Summary

As of now, Covaxin is priced at Rs 1,200 per dose while Covishield costs Rs 780 in private facilities. The prices include Rs 150 service charge. Both the vaccines are only authorised for emergency use in the country.

The price of Covishield and Covaxin, the COVID vaccines which are expected to soon get regular market approval from India’s drug regulator, is likely to be capped at Rs 275 per dose plus an additional service charge of Rs 150, official sources said. According to them, the National Pharmaceutical Pricing Authority (NPPA) has been directed to start working towards capping the price to make the vaccines affordable.

As of now, Covaxin is priced at Rs 1,200 per dose while Covishield costs Rs 780 in private facilities. The prices include Rs 150 service charge. Both the vaccines are only authorised for emergency use in the country. A Subject Expert Committee on COVID-19 of the Central Drugs Standard Control Organisation on January 19 recommended granting regular market approval to COVID vaccines Covishield and Covaxin for use in the adult population subject to certain conditions.

Also Read | Sputnik V Covid vaccine shows higher Omicron-specific antibodies than Pfizer: Study

“The NPPA has been asked to work towards capping the price of the vaccines. The price is likely to be capped at Rs 275 per dose along with an additional service charge of Rs 150,” an official source said. Prakash Kumar Singh, the director (government and regulatory affairs) at Serum Institute of India, had submitted an application to the Drugs Controller General of India on October 25 seeking regular market approval for its Covishield vaccine.

A couple of weeks ago, V Krishna Mohan, the whole-time director at Bharat Biotech, submitted complete information on the chemistry, manufacturing and controls, along with the pre-clinical and clinical data while seeking regular market authorisation for Covaxin. Covaxin and Covishield were granted Emergency Use Authorisation (EUA) on January 3 last year.

Also, catch all the live updates on COVID-19 situation with CNBC-TV18.com’s blog

Elon Musk forms several ‘X Holdings’ companies to fund potential Twitter buyout

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Thursday’s filing dispelled some doubts, though Musk still has work to do. He and his advisers will spend the coming days vetting potential investors for the equity portion of his offer, according to people familiar with the matter

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KV Prasad Journo follow politics, process in Parliament and US Congress. Former Congressional APSA-Fulbright Fellow

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index Price Change
nifty 50 ₹16,986.00 -72.15
sensex ₹1,882.60 +28.30
nifty IT ₹2,206.80 +30.85
nifty bank ₹1,318.95 -14.95
index Price Change
nifty 50 ₹16,986.00 -7.15
sensex ₹1,882.60 +8.30
nifty IT ₹2,206.80 +3.85
nifty bank ₹1,318.95 -1.95
index Price Change
nifty 50 ₹16,986.00 -72.15
sensex ₹1,882.60 +28.30
nifty IT ₹2,206.80 +30.85
nifty bank ₹1,318.95 -14.95
index Price Change
nifty 50 ₹16,986.00 -7.15
sensex ₹1,882.60 +8.30
nifty IT ₹2,206.80 +3.85
nifty bank ₹1,318.95 -1.95
index Price Change
nifty 50 ₹16,986.00 -7.15
sensex ₹1,882.60 +8.30
nifty IT ₹2,206.80 +3.85
nifty bank ₹1,318.95 -1.95

Currency

Company Price Chng %Chng
Dollar-Rupee 73.3500 0.0000 0.00
Euro-Rupee 89.0980 0.0100 0.01
Pound-Rupee 103.6360 -0.0750 -0.07
Rupee-100 Yen 0.6734 -0.0003 -0.05
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One year of vaccination: Great feat, scope for further improvement

KV Prasad Jun 13, 2022, 06:35 AM IST (Published)

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Summary

Amidst a surge in the number of cases, India has started giving booster doses of the COVID-19 vaccine to priority groups from January 10. Health and frontline workers besides people over 60 years of age with comorbidities are eligible for the booster.

India completed one year of its vaccination drive last week even as the country continues to be in the grip of a third wave of pandemic. When the pandemic had hit the country, very little was known about the virus and the vaccine. But in a very short span of time, the scientists could carve a trajectory for indigenous vaccine.

India began its vaccine campaign on January 16, 2021 and the first doses were administered to its healthcare workers, fighting the battle from the front. The drive was later expanded to cover frontline workers, followed by people above 60 years of age and those above 45 years with comorbidities. Later, the vaccine coverage was also expanded to all above 45 years of age and recently to those above 18 years of age. The country started vaccinating its teenagers between the age group 15-18 on January 3, 2022.

As on January 18, more than 158 crore vaccine doses have been administered so far under the Nationwide Vaccination Drive. Around 907 million persons 15 and older have received at least one shot, 656 million two doses, while 4. 3 million a third dose. Considering the challenges — population size, remote locations and patchy healthcare infrastructure — India’s achievement in such a short time is commendable.

Amidst a surge in the number of cases, India has started giving booster doses of the COVID-19 vaccine to priority groups from January 10. Health and frontline workers besides people over 60 years of age with comorbidities are eligible for the booster.

The booster dose that has been termed as the ‘precaution dose’ will be the same vaccine that was given for the first and the second doses. As on January 18, over 50 lakh healthcare and frontline workers besides citizens aged 60 years or above have received the precaution dose.

“I salute each and every individual who is associated with the vaccination drive. Our vaccination programme has added great strength to the fight against COVID-19. It has led to saving lives and thus protecting livelihoods,” Prime Minister Narendra Modi had tweeted on the completion of one year of the vaccination drive on January 15.

India is likely to begin inoculating children in the 12-14 age groups against Covid from March. Of the estimated 7.4 crore children in the 15-18 age bracket, over 3.45 crore have already received the first dose of Covaxin.

ALSO READ | COVID-19 health insurance: Options available, list of policies and other questions answered

India has witnessed a flurry of research activities on developing the vaccine. The country has been administering two locally made vaccines — Covaxin and Covishield since the vaccination drive kicked off in January 2021. In December, India, approved two new vaccines — Serum Institute of India’s Covovax and Biological E’s Corbevax, both authorised for restricted use in an emergency situation. There are also other candidates which are in different stages of trials in India to test safety and efficacy.

The omicron variant was first discovered in South Africa in November last year. As on January 18 around 70.54 crore total tests had been conducted so far, 16,49,143 tests conducted in the last 24 hours. The daily positivity rate stands at 14.43 percent. India’s active caseload currently stands at 17,36,628. The active cases stand at 4.62 percent. More than 8,890 Omicron cases had been detected so far.

Challenging terrain

The vaccination drive has been hamstrung with several hiccups and challenges. The drive has been dotted with challenges—population, remote terrains and anaemic infrastructure.

While India had been at the forefront of child immunisation, adult immunisation of such a grand scale was an unexplored territory. Besides the logistics pinpricks, establishing a harmonious public-private partnership was a daunting task. The success of a vaccination program of this scale also required immense collaboration between the central and state governments. An effective communication strategy and a robust awareness generation programme also helped in giving the momentum to the vaccination drive.

ALSO READ | EPFO withdrawal: How to avail COVID-19 advance twice from PF account?

The vaccines require an excellent cold chain management and the transportation of the vaccines across the length and breadth of the country was mired with hurdles. The immunisation drive also required an excellent vaccine management strategy.

Way forward

Despite the robust numbers, there is still a lot of scope to build up the data regarding vaccination. This can help to develop the future vaccines for new and other emerging variants. The Indian vaccine developers should work together to build an ecosystem that can fight the future variants.

The concept of mix and match of vaccines also needs to explored broadly to give a further fillip to the drive. Communication programmes for accelerating the vaccination should also be spruced.

—The author, Dr Vanita Srivastava, is an independent science and health writer. Views expressed are personal
Click here to read the author’s other articles

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Thursday’s filing dispelled some doubts, though Musk still has work to do. He and his advisers will spend the coming days vetting potential investors for the equity portion of his offer, according to people familiar with the matter

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index Price Change
nifty 50 ₹16,986.00 -72.15
sensex ₹1,882.60 +28.30
nifty IT ₹2,206.80 +30.85
nifty bank ₹1,318.95 -14.95
index Price Change
nifty 50 ₹16,986.00 -7.15
sensex ₹1,882.60 +8.30
nifty IT ₹2,206.80 +3.85
nifty bank ₹1,318.95 -1.95
index Price Change
nifty 50 ₹16,986.00 -72.15
sensex ₹1,882.60 +28.30
nifty IT ₹2,206.80 +30.85
nifty bank ₹1,318.95 -14.95
index Price Change
nifty 50 ₹16,986.00 -7.15
sensex ₹1,882.60 +8.30
nifty IT ₹2,206.80 +3.85
nifty bank ₹1,318.95 -1.95
index Price Change
nifty 50 ₹16,986.00 -7.15
sensex ₹1,882.60 +8.30
nifty IT ₹2,206.80 +3.85
nifty bank ₹1,318.95 -1.95

Currency

Company Price Chng %Chng
Dollar-Rupee 73.3500 0.0000 0.00
Euro-Rupee 89.0980 0.0100 0.01
Pound-Rupee 103.6360 -0.0750 -0.07
Rupee-100 Yen 0.6734 -0.0003 -0.05
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SEC recommends regular market authorisation for Covishield and Covaxin: Sources

KV Prasad Jun 13, 2022, 06:35 AM IST (Published)

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Summary

Subject Expert Committee on Friday recommended regular market authorisation to Covishield and Covaxin. SII had applied for market approval for the Covishield vaccine in December 2021 and Bharat Biotech also applied for the same a few days ago.

Drugs Controller General of India (DCGI)’s Subject Expert Committee on Friday recommended regular market authorisation for Covishield and Covaxin, official sources said.

Both the vaccines will be available at clinics and hospitals registered with CoWin, sources added.

The recommendations will be sent to DCGI for final approval. During last week’s meeting the SEC had sought more data and information from the two companies.

Also Read: Mix & Match of Covaxin, Covishield elicits 4 times antibody response

Serum Institute of India (SII) had applied for market approval for the Covishield vaccine in December 2021 and Bharat Biotech also applied for the same a few days ago.

Both Covaxin and Covishield are currently authorized for emergency use only. EUA does not represent approval of a vaccine in the full statutory term but authorises the use of an unapproved product or unapproved use of an approved product in a declared state of emergency such as a pandemic.

A market authorisation label for a vaccine means it can be authorised for use without reservations or conditions.

Also Read – Covaxin booster dose capable of neutralising Omicron and Delta variants of COVID-19: Bharat Biotech

 

Elon Musk forms several ‘X Holdings’ companies to fund potential Twitter buyout

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Thursday’s filing dispelled some doubts, though Musk still has work to do. He and his advisers will spend the coming days vetting potential investors for the equity portion of his offer, according to people familiar with the matter

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index Price Change
nifty 50 ₹16,986.00 -72.15
sensex ₹1,882.60 +28.30
nifty IT ₹2,206.80 +30.85
nifty bank ₹1,318.95 -14.95
index Price Change
nifty 50 ₹16,986.00 -7.15
sensex ₹1,882.60 +8.30
nifty IT ₹2,206.80 +3.85
nifty bank ₹1,318.95 -1.95
index Price Change
nifty 50 ₹16,986.00 -72.15
sensex ₹1,882.60 +28.30
nifty IT ₹2,206.80 +30.85
nifty bank ₹1,318.95 -14.95
index Price Change
nifty 50 ₹16,986.00 -7.15
sensex ₹1,882.60 +8.30
nifty IT ₹2,206.80 +3.85
nifty bank ₹1,318.95 -1.95
index Price Change
nifty 50 ₹16,986.00 -7.15
sensex ₹1,882.60 +8.30
nifty IT ₹2,206.80 +3.85
nifty bank ₹1,318.95 -1.95

Currency

Company Price Chng %Chng
Dollar-Rupee 73.3500 0.0000 0.00
Euro-Rupee 89.0980 0.0100 0.01
Pound-Rupee 103.6360 -0.0750 -0.07
Rupee-100 Yen 0.6734 -0.0003 -0.05
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Bharat Biotech says 15-18 year olds getting ‘unapproved COVID-19 vaccines’

KV Prasad Jun 13, 2022, 06:35 AM IST (Published)

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Summary

In a Twitter post, Bharat Biotech said its Covaxin is the only COVID-19 jab that was approved for children in the 15-18 age group in India, and asked health workers to be vigilant.

Bharat Biotech on January 18 said it is receiving several reports that children in the age group 15-18 are being administered a COVID-19 vaccine other than Covaxin. Requesting the health workers to be vigilant and ensure that only Covaxin is administered to that particular age group, Bharat Biotech in a Twitter post said its vaccine is the only approved COVID-19 jab to be administered to children in the 15-18 age group.

Also read: Covaxin for Kids: Bharat Biotech gets DGCI nod for emergency use in children aged 12 to 18 years

“We have received several additional reports of individuals in the 15-18 year age group being administered unapproved COVID-19 vaccines,” the company said. Covaxin received approval based on thorough clinical trial evaluation for safety and immunogenicity in the 2-18 years age group. Currently it is the only COVID-19 vaccine in India approved for children, it added.

Elon Musk forms several ‘X Holdings’ companies to fund potential Twitter buyout

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Thursday’s filing dispelled some doubts, though Musk still has work to do. He and his advisers will spend the coming days vetting potential investors for the equity portion of his offer, according to people familiar with the matter

 Daily Newsletter

KV Prasad Journo follow politics, process in Parliament and US Congress. Former Congressional APSA-Fulbright Fellow

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today's market

index Price Change
nifty 50 ₹16,986.00 -72.15
sensex ₹1,882.60 +28.30
nifty IT ₹2,206.80 +30.85
nifty bank ₹1,318.95 -14.95
index Price Change
nifty 50 ₹16,986.00 -7.15
sensex ₹1,882.60 +8.30
nifty IT ₹2,206.80 +3.85
nifty bank ₹1,318.95 -1.95
index Price Change
nifty 50 ₹16,986.00 -72.15
sensex ₹1,882.60 +28.30
nifty IT ₹2,206.80 +30.85
nifty bank ₹1,318.95 -14.95
index Price Change
nifty 50 ₹16,986.00 -7.15
sensex ₹1,882.60 +8.30
nifty IT ₹2,206.80 +3.85
nifty bank ₹1,318.95 -1.95
index Price Change
nifty 50 ₹16,986.00 -7.15
sensex ₹1,882.60 +8.30
nifty IT ₹2,206.80 +3.85
nifty bank ₹1,318.95 -1.95

Currency

Company Price Chng %Chng
Dollar-Rupee 73.3500 0.0000 0.00
Euro-Rupee 89.0980 0.0100 0.01
Pound-Rupee 103.6360 -0.0750 -0.07
Rupee-100 Yen 0.6734 -0.0003 -0.05
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SEC seeks more data for granting full market approval to Covishield, Covaxin: Sources

KV Prasad Jun 13, 2022, 06:35 AM IST (Published)

 Listen to the Article (6 Minutes)

Summary

SII had applied for market approval for the Covishield vaccine in December 2021 and Bharat Biotech has also applied for the same 10 days ago.

Drugs Controller General of India (DCGI)’s Subject Expert Committee on Friday sought more data from Bharat Biotech and Serum Institute of India (SII) before granting full market approval to Covaxin and Covishield, said sources.

Sources added that SII and Bharat Biotech can’t be allowed to sell Covaxin and Covishield in open market till government is mapping vaccination through specific nationwide drive via Cowin App.

Also Read: Covaxin booster dose capable of neutralising Omicron and Delta variants of COVID-19

SII had applied for market approval for the Covishield vaccine in December 2021 and Bharat Biotech has also applied for the same 10 days ago.

However, both Covaxin and Covishield are currently authorized for emergency use only. EUA does not represent approval of a vaccine in the full statutory term but authorises the use of an unapproved product or unapproved use of an approved product in a declared state of emergency such as a pandemic. A market authorisation label for a vaccine means it can be authorised for use without reservations or conditions.

Elon Musk forms several ‘X Holdings’ companies to fund potential Twitter buyout

3 Mins Read

Thursday’s filing dispelled some doubts, though Musk still has work to do. He and his advisers will spend the coming days vetting potential investors for the equity portion of his offer, according to people familiar with the matter

 Daily Newsletter

KV Prasad Journo follow politics, process in Parliament and US Congress. Former Congressional APSA-Fulbright Fellow

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today's market

index Price Change
nifty 50 ₹16,986.00 -72.15
sensex ₹1,882.60 +28.30
nifty IT ₹2,206.80 +30.85
nifty bank ₹1,318.95 -14.95
index Price Change
nifty 50 ₹16,986.00 -7.15
sensex ₹1,882.60 +8.30
nifty IT ₹2,206.80 +3.85
nifty bank ₹1,318.95 -1.95
index Price Change
nifty 50 ₹16,986.00 -72.15
sensex ₹1,882.60 +28.30
nifty IT ₹2,206.80 +30.85
nifty bank ₹1,318.95 -14.95
index Price Change
nifty 50 ₹16,986.00 -7.15
sensex ₹1,882.60 +8.30
nifty IT ₹2,206.80 +3.85
nifty bank ₹1,318.95 -1.95
index Price Change
nifty 50 ₹16,986.00 -7.15
sensex ₹1,882.60 +8.30
nifty IT ₹2,206.80 +3.85
nifty bank ₹1,318.95 -1.95

Currency

Company Price Chng %Chng
Dollar-Rupee 73.3500 0.0000 0.00
Euro-Rupee 89.0980 0.0100 0.01
Pound-Rupee 103.6360 -0.0750 -0.07
Rupee-100 Yen 0.6734 -0.0003 -0.05
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Covaxin booster dose capable of neutralising Omicron and Delta variants of COVID-19: Bharat Biotech

KV Prasad Jun 13, 2022, 06:35 AM IST (Published)

 Listen to the Article (6 Minutes)

Summary

Bharat Biotech said its booster dose of Covaxin has generated robust neutralizing antibody responses against both Omicron and Delta variants of COVID-19.

Bharat Biotech on Wednesday said its booster dose of Covaxin has generated neutralising antibody responses against both Omicron and Delta variants of COVID-19.

“A study conducted at Emory University demonstrated that subjects who received a booster dose of Covaxin (BBV152) six months after getting a primary two-dose series have witnessed neutralising of the SARS-CoV-2 Omicron and Delta variants,” the vaccine major said in a statement.

Citing the study results, Bharat Biotech noted that more than 90 percent of all individuals boosted with Covaxin showed neutralising antibodies.

“As the dominant COVID-19 variant throughout the world, Omicron poses a serious public health concern. Data from this preliminary analysis show individuals receiving a booster dose of Covaxin have a significant immune response to both the Omicron and Delta variants,” it added.

Also Read: Bharat Biotech says Covaxin safe for booster dose against Covid

“These findings suggest that a booster dose has the potential to reduce disease severity and hospitalizations,” Emory Vaccine Center Assistant Professor Mehul Suthar, who led the laboratory analysis, noted.

Last week, Bharat Biotech had said that no paracetamol or painkiller is recommended after being vaccinated with Covaxin, The company noted that Covaxin is formulated uniquely such that the same dosage can be administered to adults and children alike.

Also Read: No paracetamol, painkillers needed after getting Covaxin jab: Bharat Biotech

(With inputs from PTI)

Elon Musk forms several ‘X Holdings’ companies to fund potential Twitter buyout

3 Mins Read

Thursday’s filing dispelled some doubts, though Musk still has work to do. He and his advisers will spend the coming days vetting potential investors for the equity portion of his offer, according to people familiar with the matter

 Daily Newsletter

KV Prasad Journo follow politics, process in Parliament and US Congress. Former Congressional APSA-Fulbright Fellow

Previous Article

Oil Fluctuates as Traders Assess China’s Vow, Unrest in Libya

Next Article

Shanghai residents turn to NFTs to record COVID lockdown, combat censorship

LIVE TV

today's market

index Price Change
nifty 50 ₹16,986.00 -72.15
sensex ₹1,882.60 +28.30
nifty IT ₹2,206.80 +30.85
nifty bank ₹1,318.95 -14.95
index Price Change
nifty 50 ₹16,986.00 -7.15
sensex ₹1,882.60 +8.30
nifty IT ₹2,206.80 +3.85
nifty bank ₹1,318.95 -1.95
index Price Change
nifty 50 ₹16,986.00 -72.15
sensex ₹1,882.60 +28.30
nifty IT ₹2,206.80 +30.85
nifty bank ₹1,318.95 -14.95
index Price Change
nifty 50 ₹16,986.00 -7.15
sensex ₹1,882.60 +8.30
nifty IT ₹2,206.80 +3.85
nifty bank ₹1,318.95 -1.95
index Price Change
nifty 50 ₹16,986.00 -7.15
sensex ₹1,882.60 +8.30
nifty IT ₹2,206.80 +3.85
nifty bank ₹1,318.95 -1.95

Currency

Company Price Chng %Chng
Dollar-Rupee 73.3500 0.0000 0.00
Euro-Rupee 89.0980 0.0100 0.01
Pound-Rupee 103.6360 -0.0750 -0.07
Rupee-100 Yen 0.6734 -0.0003 -0.05
Quiz
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Should Elon Musk be able to buy Twitter?

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Bharat Biotech says Covaxin safe for booster dose against Covid

KV Prasad Jun 13, 2022, 06:35 AM IST (Published)

 Listen to the Article (6 Minutes)

Summary

Booster BBV152 vaccination is safe and may be necessary to ensure persistent immunity to prevent breakthrough infections, said Bharat Biotech.

Bharat Biotech said trials have indicated that its vaccine Covaxin is safe for booster dosage against COVID-19. The analysis showed, six months after a two-dose Covaxin (BBV152) vaccination series cell-mediated immunity and neutralising antibodies to both homologous (D614G) and heterologous strains (Alpha, Beta, Delta, and Delta plus) persisted above baseline, although the magnitude of the responses had declined, the company said.

Furthermore, neutralising antibodies against homologous and heterologous SARS-CoV-2 variants increased from 19 to 265 folds after a third vaccination, it added. Booster BBV152 vaccination is safe and may be necessary to ensure persistent immunity to prevent breakthrough infections, it added.

“These trial results provide a strong foundation towards our goal to provide Covaxin as a booster dose. Our goal of developing a global vaccine against COVID-19 has been achieved with Covaxin indicated for adults, children, two dose primary and booster doses. This enables the use of the vaccine as a universal vaccine,” Bharat Biotech Chairman and Managing Director Krishna Ella said. Further, reactogenicity after vaccine and placebo was minimal and comparable, and no serious adverse events were reported, the company said referring to the trial results.

“Based on emerging data, Bharat Biotech believes that a third dose may be beneficial to maintain the highest levels of protection,” it added. Bharat Biotech noted that Covaxin is formulated uniquely such that the same dosage can be administered to adults and children alike.

Elon Musk forms several ‘X Holdings’ companies to fund potential Twitter buyout

3 Mins Read

Thursday’s filing dispelled some doubts, though Musk still has work to do. He and his advisers will spend the coming days vetting potential investors for the equity portion of his offer, according to people familiar with the matter

 Daily Newsletter

KV Prasad Journo follow politics, process in Parliament and US Congress. Former Congressional APSA-Fulbright Fellow

Previous Article

Oil Fluctuates as Traders Assess China’s Vow, Unrest in Libya

Next Article

Shanghai residents turn to NFTs to record COVID lockdown, combat censorship

LIVE TV

today's market

index Price Change
nifty 50 ₹16,986.00 -72.15
sensex ₹1,882.60 +28.30
nifty IT ₹2,206.80 +30.85
nifty bank ₹1,318.95 -14.95
index Price Change
nifty 50 ₹16,986.00 -7.15
sensex ₹1,882.60 +8.30
nifty IT ₹2,206.80 +3.85
nifty bank ₹1,318.95 -1.95
index Price Change
nifty 50 ₹16,986.00 -72.15
sensex ₹1,882.60 +28.30
nifty IT ₹2,206.80 +30.85
nifty bank ₹1,318.95 -14.95
index Price Change
nifty 50 ₹16,986.00 -7.15
sensex ₹1,882.60 +8.30
nifty IT ₹2,206.80 +3.85
nifty bank ₹1,318.95 -1.95
index Price Change
nifty 50 ₹16,986.00 -7.15
sensex ₹1,882.60 +8.30
nifty IT ₹2,206.80 +3.85
nifty bank ₹1,318.95 -1.95

Currency

Company Price Chng %Chng
Dollar-Rupee 73.3500 0.0000 0.00
Euro-Rupee 89.0980 0.0100 0.01
Pound-Rupee 103.6360 -0.0750 -0.07
Rupee-100 Yen 0.6734 -0.0003 -0.05
Quiz
Powered by
Are you a Crypto Head? It’s time to prove it!
10 Questions · 5 Minutes
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Win WRX (WazirX token) worth Rs. 1500.
Question 1 of 5

What coins do you think will be valuable over next 3 years?

Answer Anonymously

Should Elon Musk be able to buy Twitter?

 5 Minutes Read

No paracetamol, painkillers needed after getting Covaxin jab: Bharat Biotech

KV Prasad Jun 13, 2022, 06:35 AM IST (Published)

 Listen to the Article (6 Minutes)

Summary

Paracetamol was recommended along with other COVID-19 vaccines only and is not prescribed for Covaxin, Bharat Biotech said on Wednesday.

No paracetamol or painkiller is recommended after being vaccinated with COVID-19 vaccine Covaxin, Bharat Biotech said on Wednesday. “We have received feedback that certain immunisation centres are recommending taking three paracetamol 500 mg tablets along with Covaxin for children. No paracetamol or painkillers are recommended after being vaccinated with Covaxin,” Bharat Biotech said in a Twitter post.

Through the clinical trials spanning about 30,000 individuals, approximately 10 to 20 percent have reported side effects and most of them were mild, resolved within one or two days, and did not require any medication, the company further said. Medication is recommended only after consultation with a physician, the vaccine maker said.

Paracetamol was recommended along with other COVID-19 vaccines only and is not prescribed for Covaxin, it added.

For live updates on Coronavirus, click here

Elon Musk forms several ‘X Holdings’ companies to fund potential Twitter buyout

3 Mins Read

Thursday’s filing dispelled some doubts, though Musk still has work to do. He and his advisers will spend the coming days vetting potential investors for the equity portion of his offer, according to people familiar with the matter

 Daily Newsletter

KV Prasad Journo follow politics, process in Parliament and US Congress. Former Congressional APSA-Fulbright Fellow

Previous Article

Oil Fluctuates as Traders Assess China’s Vow, Unrest in Libya

Next Article

Shanghai residents turn to NFTs to record COVID lockdown, combat censorship

LIVE TV

today's market

index Price Change
nifty 50 ₹16,986.00 -72.15
sensex ₹1,882.60 +28.30
nifty IT ₹2,206.80 +30.85
nifty bank ₹1,318.95 -14.95
index Price Change
nifty 50 ₹16,986.00 -7.15
sensex ₹1,882.60 +8.30
nifty IT ₹2,206.80 +3.85
nifty bank ₹1,318.95 -1.95
index Price Change
nifty 50 ₹16,986.00 -72.15
sensex ₹1,882.60 +28.30
nifty IT ₹2,206.80 +30.85
nifty bank ₹1,318.95 -14.95
index Price Change
nifty 50 ₹16,986.00 -7.15
sensex ₹1,882.60 +8.30
nifty IT ₹2,206.80 +3.85
nifty bank ₹1,318.95 -1.95
index Price Change
nifty 50 ₹16,986.00 -7.15
sensex ₹1,882.60 +8.30
nifty IT ₹2,206.80 +3.85
nifty bank ₹1,318.95 -1.95

Currency

Company Price Chng %Chng
Dollar-Rupee 73.3500 0.0000 0.00
Euro-Rupee 89.0980 0.0100 0.01
Pound-Rupee 103.6360 -0.0750 -0.07
Rupee-100 Yen 0.6734 -0.0003 -0.05
Quiz
Powered by
Are you a Crypto Head? It’s time to prove it!
10 Questions · 5 Minutes
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Win WRX (WazirX token) worth Rs. 1500.
Question 1 of 5

What coins do you think will be valuable over next 3 years?

Answer Anonymously

Should Elon Musk be able to buy Twitter?