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Serum Institute of India says its prioritising domestic vaccine needs

KV Prasad Jun 13, 2022, 06:35 AM IST (Published)

 Listen to the Article (6 Minutes)

Summary

Based in the western Indian city of Pune, the company is manufacturing the Oxford University/AstraZeneca COVID-19 vaccine.

Serum Institute of India (SII), the world’s biggest vaccine maker by volume, on Sunday asked for patience from foreign governments awaiting their supply of COVID-19 shots, saying it had been directed to prioritise India’s requirements.

“…I humbly request you to please be patient,” SII’s Chief Executive Adar Poonawalla said in a tweet adding the company “has been directed to prioritise the huge needs of India and along with that balance the needs of the rest of the world.”

“We are trying our best,” Poonawalla said.

Based in the western Indian city of Pune, the company is manufacturing the Oxford University/AstraZeneca COVID-19 vaccine, one of the two shots that India is using to initially vaccinate some 300 million people as part of a national inoculation drive.

Many low-and middle-income countries, ranging from Bangladesh to Brazil, are depending on SII’s AstraZeneca vaccine, branded COVISHIELD by the Indian company.

But demand is growing, including from Western countries like Canada, where Poonawalla has promised to deliver the COVISHIELD vaccine next month.

Britain’s drug regulator is also auditing manufacturing processes at SII, potentially paving the way for the COVISHIELD vaccine to be shipped from there to the UK and other countries..

Indian Prime Minister Narendra Modi’s government has come under criticism for the slow take-off of its vaccination drive but health authorities are preparing to expand the number of inoculation substantially in coming weeks.

India has vaccinated around 11 million people since mid-January.

With more than 10.9 million confirmed infections, India has the world’s second-highest number of COVID-19 cases, behind only the United States.

The country is currently reporting around 12,000 new infections on average each day, a fraction of its peak from last September, according to a Reuters analysis.

But federal health authorities on Sunday said they had written to some states that are currently seeing a surge in cases, asking them to improve overall testing, surveillance and monitoring of COVID-19 mutations.

 

 

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index Price Change
nifty 50 ₹16,986.00 -72.15
sensex ₹1,882.60 +28.30
nifty IT ₹2,206.80 +30.85
nifty bank ₹1,318.95 -14.95
index Price Change
nifty 50 ₹16,986.00 -7.15
sensex ₹1,882.60 +8.30
nifty IT ₹2,206.80 +3.85
nifty bank ₹1,318.95 -1.95
index Price Change
nifty 50 ₹16,986.00 -72.15
sensex ₹1,882.60 +28.30
nifty IT ₹2,206.80 +30.85
nifty bank ₹1,318.95 -14.95
index Price Change
nifty 50 ₹16,986.00 -7.15
sensex ₹1,882.60 +8.30
nifty IT ₹2,206.80 +3.85
nifty bank ₹1,318.95 -1.95
index Price Change
nifty 50 ₹16,986.00 -7.15
sensex ₹1,882.60 +8.30
nifty IT ₹2,206.80 +3.85
nifty bank ₹1,318.95 -1.95

Currency

Company Price Chng %Chng
Dollar-Rupee 73.3500 0.0000 0.00
Euro-Rupee 89.0980 0.0100 0.01
Pound-Rupee 103.6360 -0.0750 -0.07
Rupee-100 Yen 0.6734 -0.0003 -0.05
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EXPLAINER: Japan begins vaccination drive, but why so late?

KV Prasad Jun 13, 2022, 06:35 AM IST (Published)

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Summary

Despite its late start, Japan was quick to strike deals with Pfizer and two other companies, AstraZeneca and Moderna, in July when the vaccines were still being developed.

Japan rolls out its COVID-19 vaccination campaign Wednesday after the government gave belated first approval to a shot co-developed by Pfizer Inc. that the U.S. and many other countries started using two months ago.

Some in Japan, where relatively rare side effects from vaccines tend to be played up, are in no hurry to get the shot. That reluctance could prove to be a big problem for the Tokyo Olympics scheduled for this summer after a year’s delay. Vaccinations are considered a key to holding the games.

With domestic vaccine development still in its early stages, import-reliant Japan faces uncertainty in its supply. It’s also unclear if the already-strained Japanese health care system will be able to treat the extra visitors during the games as they juggle local patients and the mass inoculations.

The AP looks at why Japan, the world’s third-biggest economy, is so late in pursuing coronavirus vaccinations.

WHY THE DELAY?

It’s mostly because the government asked for clinical testing in Japan in addition to Pfizer’s multinational tests, which did not include Japan.

Dozens of countries accepted the results of the Pfizer tests released in November and moved ahead. Pfizer applied for emergency approval in Japan in December, based on the overseas data, but Tokyo waited for results of Japanese tests submitted in late January before giving a green light on Sunday.

This all happened in two months, much faster that the one-year average that is usual for Japan, known for being cautious and bogged down in bureaucracy.

The approval process for another supplier, AstraZeneca, only started recently, while a third, Moderna Inc. hasn’t applied yet in Japan.

WHY DID JAPAN ASK FOR MORE DATA?

People in Japan are often skeptical about vaccines, and officials felt they needed to address safety concerns thoroughly.

Health Minister Norihisa Tamura said last week that Asians comprised only a small percent of Pfizer tests, which were conducted from July to November on about 44,000 people in six countries.

Even so, that means the data included samples of about 2,000 Asians. Some critics are questioning whether the additional tests on only 160 Japanese people added anything except more delay.

Taro Kono, administrative reform minister for vaccinations, defended the delay. It was more important for the government to show the Japanese people that everything was done” to encourage taking the vaccines, he said.

WHY IS CONFIDENCE SO LOW IN JAPAN?

Japan’s mistrust of vaccines is decades old. Many people have a vague unease about vaccines, partly because their side effects have often been played up.

In the 1990s, the government scrapped mandatory vaccinations after a court ruling held it responsible for side effects linked to several of them.

More recently, Japan stopped recommending the human papillomavirus, or HPV, vaccine after media reports of alleged side effects, renewing worries despite the vaccine’s widespread use overseas as safe and effective protection for cervical cancer.

A recent Mainichi newspaper survey showed that fewer than 40 percent of the respondents are eager to get their coronavirus shots right away, while about 60 percent said they will wait and see.

WHAT IS JAPAN’S VACCINATION TIMELINE?

About 40,000 front-line medical workers treating COVID-19 patients are slated to get their first shots of the Pfizer vaccine at 100 hospitals. Half of them will participate in a survey of side effects and subsequent health checks to try to ease public safety concern.

About 3.7 million other medical workers will be next. The elderly are expected to get their turn in April, ahead of those with underlying health issues.

It will be about June by the time those older than 16 will be eligible.

DOES JAPAN HAVE ENOUGH VACCINE?

Despite its late start, Japan was quick to strike deals with Pfizer and two other companies, AstraZeneca and Moderna, in July when the vaccines were still being developed.

Japan has secured 344 million doses, enough to cover its entire population, through the end of this year. That includes 144 million doses from Pfizer, 120 million from AstraZeneca and 50 million from Moderna.

Japan pledged to secure doses for its entire population by June, but the prospects are unsure amid shortages in Europe where much of Pfizer and AstraZeneca supplies are produced.

Taro Kono, the minister in charge of vaccinations, on Tuesday described the prospects of getting the vaccines in time as difficult.” Though he expressed optimism, he said supplies from Europe will determine the progress of the campaign in Japan.

IS JAPAN DEVELOPING ITS OWN VACCINES?

Several Japanese companies and research organizations are developing coronavirus vaccines, but they are in the early stages.

Takeda Pharmaceutical Co. will distribute the Moderna vaccine and produce the Novavax vaccine at home, and JCR Pharmaceuticals Co. will produce the AstraZeneca vaccine under a licensing deal.

Only AstraZeneca is currently in the approval process.

Experts say vaccine development in Japan has become an unpopular research area because of risks, the time-consuming process and a lack of government funding.

Shigeru Omi, the head of the government coronavirus task force, has cited a lack of global competitiveness by Japanese pharmaceutical companies as a reason for the delayed rollout.

Elon Musk forms several ‘X Holdings’ companies to fund potential Twitter buyout

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Thursday’s filing dispelled some doubts, though Musk still has work to do. He and his advisers will spend the coming days vetting potential investors for the equity portion of his offer, according to people familiar with the matter

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index Price Change
nifty 50 ₹16,986.00 -72.15
sensex ₹1,882.60 +28.30
nifty IT ₹2,206.80 +30.85
nifty bank ₹1,318.95 -14.95
index Price Change
nifty 50 ₹16,986.00 -7.15
sensex ₹1,882.60 +8.30
nifty IT ₹2,206.80 +3.85
nifty bank ₹1,318.95 -1.95
index Price Change
nifty 50 ₹16,986.00 -72.15
sensex ₹1,882.60 +28.30
nifty IT ₹2,206.80 +30.85
nifty bank ₹1,318.95 -14.95
index Price Change
nifty 50 ₹16,986.00 -7.15
sensex ₹1,882.60 +8.30
nifty IT ₹2,206.80 +3.85
nifty bank ₹1,318.95 -1.95
index Price Change
nifty 50 ₹16,986.00 -7.15
sensex ₹1,882.60 +8.30
nifty IT ₹2,206.80 +3.85
nifty bank ₹1,318.95 -1.95

Currency

Company Price Chng %Chng
Dollar-Rupee 73.3500 0.0000 0.00
Euro-Rupee 89.0980 0.0100 0.01
Pound-Rupee 103.6360 -0.0750 -0.07
Rupee-100 Yen 0.6734 -0.0003 -0.05
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Australia approves AstraZeneca vaccine for use

KV Prasad Jun 13, 2022, 06:35 AM IST (Published)

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Summary

Prime Minister Scott Morrison said the Therapeutic Goods Administration, the regulator, found the AstraZeneca vaccine was safe and effective.

Australia’s regulator on Tuesday approved the AstraZeneca vaccine as its second for use against COVID-19. Pfizer’s product will be available in Australia next week. It will be given in two doses three weeks apart, while AstraZeneca’s will be administered in two doses 12 weeks apart.

Prime Minister Scott Morrison said the Therapeutic Goods Administration, the regulator, found the AstraZeneca vaccine was safe and effective. Health Minister Greg Hunt said the AstraZeneca vaccine will prevent serious COVID-19 illness.

Morrison will be vaccinated with the Pfizer product and Hunt with AstraZeneca in a demonstration of confidence in both vaccines. Australia has contracted 53.8 million doses of the AstraZeneca vaccine, and 50 million of those will be manufactured in Australia.

The government has also secured 20 million Pfizer vaccines for a population of 26 million.

Click here: For the latest news and updates on COVID-19

Elon Musk forms several ‘X Holdings’ companies to fund potential Twitter buyout

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Thursday’s filing dispelled some doubts, though Musk still has work to do. He and his advisers will spend the coming days vetting potential investors for the equity portion of his offer, according to people familiar with the matter

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KV Prasad Journo follow politics, process in Parliament and US Congress. Former Congressional APSA-Fulbright Fellow

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index Price Change
nifty 50 ₹16,986.00 -72.15
sensex ₹1,882.60 +28.30
nifty IT ₹2,206.80 +30.85
nifty bank ₹1,318.95 -14.95
index Price Change
nifty 50 ₹16,986.00 -7.15
sensex ₹1,882.60 +8.30
nifty IT ₹2,206.80 +3.85
nifty bank ₹1,318.95 -1.95
index Price Change
nifty 50 ₹16,986.00 -72.15
sensex ₹1,882.60 +28.30
nifty IT ₹2,206.80 +30.85
nifty bank ₹1,318.95 -14.95
index Price Change
nifty 50 ₹16,986.00 -7.15
sensex ₹1,882.60 +8.30
nifty IT ₹2,206.80 +3.85
nifty bank ₹1,318.95 -1.95
index Price Change
nifty 50 ₹16,986.00 -7.15
sensex ₹1,882.60 +8.30
nifty IT ₹2,206.80 +3.85
nifty bank ₹1,318.95 -1.95

Currency

Company Price Chng %Chng
Dollar-Rupee 73.3500 0.0000 0.00
Euro-Rupee 89.0980 0.0100 0.01
Pound-Rupee 103.6360 -0.0750 -0.07
Rupee-100 Yen 0.6734 -0.0003 -0.05
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UK says Astrazeneca vaccine prevents COVID-19 death as South Africa halts shots

KV Prasad Jun 13, 2022, 06:35 AM IST (Published)

 Listen to the Article (6 Minutes)

Summary

”There is no evidence that this vaccine is not effective in preventing hospitalisation and severe illness and death, which ultimately is what we’re seeking with these vaccines today,” Britain’s Edward Argar told Sky.

There is no evidence that the Astrazeneca vaccine does not prevent death or serious illness, and South Africa has only imposed a temporary halt on using the vaccine, a British junior health minister said on Monday.

South Africa will put on hold use of AstraZeneca’s COVID-19 shot in its vaccination programme after data showed it gave minimal protection against mild-to-moderate infection caused by the country’s dominant coronavirus variant.

”There is no evidence that this vaccine is not effective in preventing hospitalisation and severe illness and death, which ultimately is what we’re seeking with these vaccines today,” Britain’s Edward Argar told Sky.

”The dominant strains in this country are not the South African strain, there are a small number of cases of that, the dominant strains here are the historic one we’ve had, and then the Kent variant, against which this vaccine is highly effective.”

Click here: For the latest news and updates on COVID-19

Elon Musk forms several ‘X Holdings’ companies to fund potential Twitter buyout

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Thursday’s filing dispelled some doubts, though Musk still has work to do. He and his advisers will spend the coming days vetting potential investors for the equity portion of his offer, according to people familiar with the matter

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KV Prasad Journo follow politics, process in Parliament and US Congress. Former Congressional APSA-Fulbright Fellow

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today's market

index Price Change
nifty 50 ₹16,986.00 -72.15
sensex ₹1,882.60 +28.30
nifty IT ₹2,206.80 +30.85
nifty bank ₹1,318.95 -14.95
index Price Change
nifty 50 ₹16,986.00 -7.15
sensex ₹1,882.60 +8.30
nifty IT ₹2,206.80 +3.85
nifty bank ₹1,318.95 -1.95
index Price Change
nifty 50 ₹16,986.00 -72.15
sensex ₹1,882.60 +28.30
nifty IT ₹2,206.80 +30.85
nifty bank ₹1,318.95 -14.95
index Price Change
nifty 50 ₹16,986.00 -7.15
sensex ₹1,882.60 +8.30
nifty IT ₹2,206.80 +3.85
nifty bank ₹1,318.95 -1.95
index Price Change
nifty 50 ₹16,986.00 -7.15
sensex ₹1,882.60 +8.30
nifty IT ₹2,206.80 +3.85
nifty bank ₹1,318.95 -1.95

Currency

Company Price Chng %Chng
Dollar-Rupee 73.3500 0.0000 0.00
Euro-Rupee 89.0980 0.0100 0.01
Pound-Rupee 103.6360 -0.0750 -0.07
Rupee-100 Yen 0.6734 -0.0003 -0.05
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AstraZeneca vaccine drastically cut COVID-19 virus transmission, says study

KV Prasad Jun 13, 2022, 06:35 AM IST (Published)

 Listen to the Article (6 Minutes)

Summary

After measuring the impact on transmission, the researchers found a 67 percent reduction in positive swabs among those vaccinated

Researchers at the University of Oxford have said that the AstraZeneca vaccine, developed jointly by the university and the British–Swedish pharmaceutical company, can drastically cut the transmission of COVID-19 virus.

According to a New York Times report, the study revealed that not only does the vaccine protect people from serious illness and death, but substantially slows the transmission of the virus.

The report added that researchers, after measuring the impact on transmission — by swabbing participants every week seeking to detect signs of the virus — found a 67 percent reduction in positive swabs among those vaccinated.

“We now know that the Oxford vaccine also reduces transmission and that will help us all get out of this pandemic…(this) should give everyone confidence that this jab works not only to keep you safe but to keep you from passing on the virus to others,” Matt Hancock, Health Secretary of Britain told BBC.

Data further strengthened the credibility and support of the AstraZeneca vaccine. A study from 2020 found that the vaccine was 62 percent effective when given as two standard-strength doses and thus placing the vaccine’s efficacy at 90 percent when the first dose of the vaccine was given at half-strength.

The study is expected to arm AstraZeneca with enough safety data to allow it by around early March to seek authorisation to provide the vaccine for emergency use. It is also a boost for India’s fight against the virus, given the fact that the AstraZeneca vaccine is one of the two vaccines approved by the government for treatment against the pandemic.

Elon Musk forms several ‘X Holdings’ companies to fund potential Twitter buyout

3 Mins Read

Thursday’s filing dispelled some doubts, though Musk still has work to do. He and his advisers will spend the coming days vetting potential investors for the equity portion of his offer, according to people familiar with the matter

 Daily Newsletter

KV Prasad Journo follow politics, process in Parliament and US Congress. Former Congressional APSA-Fulbright Fellow

Previous Article

Oil Fluctuates as Traders Assess China’s Vow, Unrest in Libya

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today's market

index Price Change
nifty 50 ₹16,986.00 -72.15
sensex ₹1,882.60 +28.30
nifty IT ₹2,206.80 +30.85
nifty bank ₹1,318.95 -14.95
index Price Change
nifty 50 ₹16,986.00 -7.15
sensex ₹1,882.60 +8.30
nifty IT ₹2,206.80 +3.85
nifty bank ₹1,318.95 -1.95
index Price Change
nifty 50 ₹16,986.00 -72.15
sensex ₹1,882.60 +28.30
nifty IT ₹2,206.80 +30.85
nifty bank ₹1,318.95 -14.95
index Price Change
nifty 50 ₹16,986.00 -7.15
sensex ₹1,882.60 +8.30
nifty IT ₹2,206.80 +3.85
nifty bank ₹1,318.95 -1.95
index Price Change
nifty 50 ₹16,986.00 -7.15
sensex ₹1,882.60 +8.30
nifty IT ₹2,206.80 +3.85
nifty bank ₹1,318.95 -1.95

Currency

Company Price Chng %Chng
Dollar-Rupee 73.3500 0.0000 0.00
Euro-Rupee 89.0980 0.0100 0.01
Pound-Rupee 103.6360 -0.0750 -0.07
Rupee-100 Yen 0.6734 -0.0003 -0.05
Quiz
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Should Elon Musk be able to buy Twitter?